‘Saved Configurations’ are sets of saved analysis settings that have been optimized for distinct purposes.
Discovery
Favors shorter pathways, allowing for expensive starting materials
Use for: finding short syntheses to make small and mid-sized molecules
Optimization
Favors convergent pathways using less expensive starting materials, while trying to keep the number of steps as few as possible
Use for: optimizing synthesis for small and mid-sized molecules
Natural Products
Similar to ‘Optimization’, while allowing pricier starting materials, relaxing selectivity penalty and protection requirements, and letting the analysis run longer
Use for: natural products, large molecules, molecules with multiple chiral centers, and other complex molecules
General
Returns balanced pathways that favor less expensive starting materials; these conditions are similar to the default conditions used in previous versions of SYNTHIA™
Use for: finding diverse and efficient pathways for most small and mid-sized molecules, a good place to start
Note: See “Customize Analysis Settings” to learn how to customize, save, and favor your analysis settings.