Release 5.0 - December 2019

We are constantly working to improve your experience with SYNTHIA™ Retrosynthesis Software. Here is a summary of what has changed.

What’s New

 
  • Experience the new iteration-based limit for completing an analysis
  • Copy structures and reactions directly from their information cards, paste them in your favorite molecule editor
  • Sort your results by number of steps
  • Generate a PDF report in one click
  • Find hyperlinks for references and commercial compounds in your PDF report
  • Drag and drop your analysis in your favorite folder
  • Turn off the email notification for completed analyses
  • Add your own company owned inventory to SYNTHIA™ (Contact the SYNTHIA™ commercial team for more information)

 

Fixes and Improvements

 
  • Overall improvement of performance and speed
  • Pricing update for commercial compounds

 

Chemistry

6800 new expert rules have been added, covering reactions such as:

  • Intramolecular Heck cyclization reactions
  • Stereoselective Heck reactions
  • Conia-Ene cyclization reactions
  • Intramolecular alkylation of ketones and esters
  • Alkylation of indoles with alcohols,
  • Synthesis of pyrido[2,3-d]pyrimidines
  • Synthesis of fused 1,2,4-triazoles
  • Synthesis of (Z)-Fluoroalkenes via a Nozaki-Hiyama-Kishi Reaction
  • Japp Klingemann reactions