Release 5.1 - February 2020

We are constantly working to improve your experience with SYNTHIA™ Retrosynthesis Software. Here is a summary of what has changed.

What’s New

 
  • Easily hide substructures in the scoring functions
  • Find more buyable starting materials with the addition of the Aldrich Market Select catalog covering over 4 million compounds from reliable suppliers
  • Check the new information banner for downtime notifications
  • Stop your analysis directly from the dashboard

Aldrich Market Select

 

Fixes and Improvements

 
  • Improved handling of ‘Not Reaction Center’ (Do Not Cut) bonds
  • Faster generation of Similar Reactions reports
  • Fixed PDF reports export

 

Chemistry

3700 new expert rules have been added, covering reactions such as:

  • Stereoselective radical cyclisation
  • Stereoselective alkylation of esters
  • Base induced ring opening of epoxides
  • N-nitration of amines and amides
  • Organocatalytic [3+3]cycloaddition
  • Photocatalytic Decarboxylative Conjugate Addition
  • Tandem Michael addition-Smiles rearrangement