Release 5.5 - March 2021

We are constantly working to improve your experience with SYNTHIA™ Retrosynthesis Software. Here is a summary of what has changed.

What’s New

Access our new Learning Center, where you can find training videos, detailed user manuals, and featured tips and tricks
Improved search algorithm designed to increase diversity in your Automatic Retrosynthesis results

Fixes and Improvements

Updated commercial compounds catalogs
Improved search by name for target molecule
Added support for non-Latin characters in inventory

Chemistry

1050 new expert rules have been added, covering reactions such as:

Synthesis of pyridones from pyrones
Asymmetric Simmons-Smith reaction
Synthesis of 2-iminothiazolidin-4-ones
Photoredox pentafluoroethylation of aryl bromides
Synthesis of 1,2,4-triazoles
Synthesis of alpha-oxoketene S,S-acetals
[4+2] cyclization of ketene dithioacetals with acyl chlorides
Ohira-Bestmann reaction
Opening of 2H-cyclopenta[6]furanones with organocopper reagents
Trifluoromethoxylation of aromatic diazonium salts
Trifluoromethylation of phenols
Asymmetric acyl-Strecker reaction

Version 5.5.0 of SYNTHIA™ has been tested with Chrome version 88.0.4324.182 on Windows 10, and Chrome versions 84.0.4147.89, 88.0.4324.150 and 88.0.4324.182 on Mac OS Catalina 10.15.7

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