A Reaction Data File (RDF) saves pathways as a list of records, with each record representing a reaction. The reactions are saved in mol file format. Their associated data, such as reaction name, typical conditions, and illustrative references, will also be included in the file.
RDFs can be opened in Excel with the help of a proper add-in (such as JChem or ChemFinder for Excel), or in applications such as MarvinView or ChemFinder.