Similar Reactions

Select this option to search the published reaction database for similar reactions that may have appeared in scientific literature. If the proposed transformation is found on similar substrates, these reactions will be listed, along with the name of the article, the percent similarity to the proposed transformation, the published yield and reaction conditions, and the reference.

The similarity score is expressed by the Tanimoto coefficient calculated from comparing the degree of similarity between structure fingerprints from the proposed reaction and published reactions. It ranges from 0 for no similarity to 1 for an exact match.